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1

Analysis of DNA single-strand breaks in human venous blood: A technique which does not require isolation of white blood cells

Jan Georg Hengstler, Jürgen Fuchs, Berno Tanner, Barbara Oesch-Bartlomowicz, Cornelia Hölz, Franz Oesch

Journal:

Environmental and Molecular Mutagenesis

Year:

1997

Language:

english

File:

PDF, 72 KB

english, 1997

2

A Multiplex Polymerase Chain Reaction Protocol for the Simultaneous Analysis of the GlutathioneS-Transferase GSTM1 and GSTT1 Polymorphisms

Michael Arand, Roland Mühlbauer, Jan Hengstler, Elke Jäger, Jürgen Fuchs, Lars Winkler, Franz Oesch

Journal:

Analytical Biochemistry

Year:

1996

Language:

english

File:

PDF, 73 KB

english, 1996

3

Carcinogenicity categorization of chemicals—new aspects to be considered in a European perspective

Hermann M Bolt, Heidi Foth, Jan G Hengstler, Gisela H Degen

Journal:

Toxicology Letters

Year:

2004

Language:

english

File:

PDF, 153 KB

english, 2004

4

CRYOPRESERVED PRIMARY HEPATOCYTES AS A CONSTANTLY AVAILABLE IN VITRO MODEL FOR THE EVALUATION OF HUMAN AND ANIMAL DRUG METABOLISM AND ENZYME INDUCTION*

HENGSTLER, JAN G., UTESCH, D., STEINBERG, P., PLATT, K. L., DIENER, B., RINGEL, M., SWALES, N., FISCHER, T., BIEFANG, K., GERL, M., BÖTTGER, T., OESCH, F.

Journal:

Drug Metabolism Reviews

Year:

2000

Language:

english

File:

PDF, 877 KB

english, 2000

5

Allowing pseudoscience into EU risk assessment processes is eroding public trust in science experts and in science as a whole: the bigger picture

Dietrich, Daniel R., Dekant, Wolfgang, Greim, Helmut, Heslop-Harrison, Pat, Berry, Sir Colin, Boobis, Alan, Hengstler, Jan, Sharpe, Richard

Journal:

Chemico-Biological Interactions

Year:

2016

Language:

english

File:

PDF, 982 KB

english, 2016

6

Metabolic profiling ofob/obmouse fatty liver using HR-MAS1H-NMR combined with gene expression analysis reveals alterations in betaine metabolism and the transsulfuration pathway

Gogiashvili, Mikheil, Edlund, Karolina, Gianmoena, Kathrin, Marchan, Rosemarie, Brik, Alexander, Andersson, Jan T., Lambert, Jörg, Madjar, Katrin, Hellwig, Birte, Rahnenführer, Jörg, Hengstler, Jan G.

Journal:

Analytical and Bioanalytical Chemistry

Year:

2017

Language:

english

File:

PDF, 2.70 MB

english, 2017

7

Long-term simulation of lead concentrations in agricultural soils in relation to human adverse health effects

Schupp, Thomas, Damm, Georg, Foth, Heidi, Freyberger, Alexius, Gebel, Thomas, Gundert-Remy, Ursula, Hengstler, Jan G., Mangerich, Aswin, Partosch, Falko, RÃ¶hl, Claudia, Wollin, Klaus-Michael

Journal:

Archives of Toxicology

Year:

2020

File:

PDF, 1003 KB

2020

8

mdm2 mRNA expression is associated with survival in ovarian cancer

Berno Tanner, Jan Georg Hengstler, Silke Laubscher, Rolf Meinert, Franz Oesch, Wolfgang Weikel, Paul Georg Knapstein, Roger Becker

Journal:

International Journal of Cancer

Year:

1997

Language:

english

File:

PDF, 125 KB

english, 1997

9

Activity of O6-methylguanine-DNA methyltransferase in relation to p53 status and therapeutic response in ovarian cancer

Jan G. Hengstler, Berno Tanner, Lars Möller, Rolf Meinert, Bernd Kaina

Journal:

International Journal of Cancer

Year:

1999

Language:

english

File:

PDF, 216 KB

english, 1999

10

Recombinant expression of human microsomal epoxide hydrolase protects V79 Chinese hamster cells from styrene oxide- but not from ethylene oxide-induced DNA strand breaks

María Elena Herrero, Michael Arand, Jan Georg Hengstler, Franz Oesch

Journal:

Environmental and Molecular Mutagenesis

Year:

1997

Language:

english

File:

PDF, 281 KB

english, 1997

11

Could treatment with neohepatocytes benefit patients with decompensated chronic liver disease?

James A. Hutchinson, Paloma Riquelme, Judith Wundt, Jan G. Hengstler, Fred Fändrich, Hendrik Ungefroren

Journal:

American Journal of Hematology

Year:

2007

Language:

english

File:

PDF, 100 KB

english, 2007

12

Extracellular matrix modulates sensitivity of hepatocytes to fibroblastoid dedifferentiation and transforming growth factor β–induced apoptosis

Patricio Godoy, Jan G. Hengstler, Iryna Ilkavets, Christoph Meyer, Anastasia Bachmann, Alexandra Müller, Gregor Tuschl, Stefan O. Mueller, Steven Dooley

Journal:

Year:

2009

Language:

english

File:

PDF, 7.37 MB

english, 2009

13

Loss of tumor suppressor protein PTEN during renal carcinogenesis

Walburgis Brenner, Gloria Färber, Thomas Herget, Hans-Anton Lehr, Jan G. Hengstler, Joachim W. Thüroff

Journal:

International Journal of Cancer

Year:

2002

Language:

english

File:

PDF, 1.51 MB

english, 2002

14

c-erbB-2 Expression in small-cell lung cancer is associated with poor prognosis

Patrick Micke, Jan Georg Hengstler, Roser Ros, Fernando Bittinger, Tsegay Metz, Susanne Gebhard, Kai Michael Beeh, Franz Oesch, Roland Buhl

Journal:

International Journal of Cancer

Year:

2001

Language:

english

File:

PDF, 277 KB

english, 2001

15

cAMP-dependent phosphorylation of CYP2B1 as a functional switch for cyclophosphamide activation and its hormonal control in vitro and in vivo

Barbara Oesch-Bartlomowicz, Bernd Richter, Roger Becker, Stephan Vogel, Palghat R. Padma, Jan-Georg Hengstler, Franz Oesch

Journal:

International Journal of Cancer

Year:

2001

Language:

english

File:

PDF, 200 KB

english, 2001

16

SPOC1, a novel PHD-finger protein: Association with residual disease and survival in ovarian cancer

Gerrit Mohrmann, Jan G. Hengstler, Thomas G. Hofmann, Sabine U. Endele, Brendan Lee, Christiane Stelzer, Bernhard Zabel, Juergen Brieger, Dirk Hasenclever, Berno Tanner, Jens Sagemueller, Jalid Sehoul

Journal:

International Journal of Cancer

Year:

2005

Language:

english

File:

PDF, 397 KB

english, 2005

17

Human sulphotransferases are involved in the activation of aristolochic acids and are expressed in renal target tissue

Walter Meinl, Ulrike Pabel, Mandy Osterloh-Quiroz, Jan G. Hengstler, Hansruedi Glatt

Journal:

International Journal of Cancer

Year:

2006

Language:

english

File:

PDF, 164 KB

english, 2006

18

Lack of mutagenic and co-mutagenic effects of magnetic fields during magnetic resonance imaging

Wolfgang G. Schreiber, Elke M. Teichmann, Ilka Schiffer, Jochem Hast, Wahida Akbari, Hildegart Georgi, Robert Graf, Michael Hehn, Hans W. Spieβ, Manfred Thelen, Franz Oesch, Jan G. Hengstler

Journal:

Journal of Magnetic Resonance Imaging

Year:

2001

Language:

english

File:

PDF, 155 KB

english, 2001

19

Lysophosphatidylethanolamine is – in contrast to – choline – generated under in vivo conditions exclusively by phospholipase A2 but not by hypochlorous acid

Celestina Schober, Jürgen Schiller, Franziska Pinker, Jan G. Hengstler, Beate Fuchs

Journal:

Bioorganic Chemistry

Year:

2009

Language:

english

File:

PDF, 1.06 MB

english, 2009

20

Evaluation of carbon tetrachloride-induced stress on rat hepatocytes by 31P NMR and MALDI-TOF mass spectrometry: lysophosphatidylcholine generation from unsaturated phosphatidylcholines

Alexander Bauer, Anika Schumann, Matthias Gilbert, Christian Wilhelm, Jan G. Hengstler, Jürgen Schiller, Beate Fuchs

Journal:

Chemistry and Physics of Lipids

Year:

2009

Language:

english

File:

PDF, 617 KB

english, 2009

21

Oncogene-mediated changes in lipid metabolism in breast cancer cells

Cristina Cadenas, Alice Langer, Eva-Maria Hein, Heiko Hayen, Matthias Hermes, Markus Schug, Jan Hengstler

Journal:

Chemistry and Physics of Lipids

Year:

2009

Language:

english

File:

PDF, 57 KB

english, 2009

22

Maximum exposure levels for xylene, formaldehyde and acetaldehyde in cars

Thomas Schupp, Hermann M. Bolt, Jan G. Hengstler

Journal:

Year:

2005

Language:

english

File:

PDF, 222 KB

english, 2005

23

Enzyme induction in cryopreserved human hepatocyte cultures

Sabine Kafert-Kasting, Krassimira Alexandrova, Marc Barthold, Britta Laube, Gerhard Friedrich, Lubomir Arseniev, Jan G. Hengstler

Journal:

Year:

2006

Language:

english

File:

PDF, 583 KB

english, 2006

24

Tumor cell specific toxicity of Inula helenium extracts

David C. Dorn, Maja Alexenizer, Jan G. Hengstler, August Dorn

Journal:

Phytotherapy Research

Year:

2006

Language:

english

File:

PDF, 1.09 MB

english, 2006

25

P2Y1 receptors inhibit both strength and plasticity of glutamatergic synaptic neurotransmission in the rat prefrontal cortex

Segundo J. Guzman, Zoltan Gerevich, Jan G. Hengstler, Peter Illes, Werner Kleemann

Journal:

Year:

2005

Language:

english

File:

PDF, 149 KB

english, 2005

26

Primary DNA damage in peripheral mononuclear blood cells of workers exposed to bitumen-based products

Juergen Fuchs, Jan Georg Hengstler, Gerd Boettler Franz Oesch

Journal:

International Archives of Occupational and Environmental Health

Year:

1996

Language:

english

File:

PDF, 672 KB

english, 1996

27

DNA single strand break analysis in mononuclear blood cells of petrol pump attendants

Franz Oesch, Juergen Fuchs, Juergen Vaupel, Jan Georg Hengstler

Journal:

International Archives of Occupational and Environmental Health

Year:

1995

Language:

english

File:

PDF, 527 KB

english, 1995

28

Perfluorinated compounds (PFC) hit the headlines

Peter H. Roos, Jürgen Angerer, Hermann Dieter, Michael Wilhelm, Detlef Wölfle, Jan G. Hengstler

Journal:

Archives of Toxicology

Year:

2008

Language:

english

File:

PDF, 217 KB

english, 2008

29

Developments in industrial and occupational toxicology: REACH, toxicogenomics, mycotoxins, lead, asbestos, boron, bitumen, deletions polymorphisms and SNP interactions

Gisela H. Degen, Jan G. Hengstler

Journal:

Archives of Toxicology

Year:

2008

Language:

english

File:

PDF, 372 KB

english, 2008

30

Induction and control of oxidative stress

Jan G. Hengstler, Hermann M. Bolt

Journal:

Archives of Toxicology

Year:

2007

Language:

english

File:

PDF, 149 KB

english, 2007

31

Addendum

Jan G. Hengstler

Journal:

Archives of Toxicology

Year:

2008

Language:

english

File:

PDF, 149 KB

english, 2008

32

Distinct subtypes of urinary bladder epithelial cells with inducible and non-inducible cytochrome P450 1A1

Sabine Plöttner, Silvia Selinski, Hermann M. Bolt, Gisela H. Degen, Jan G. Hengstler, Peter H. Roos, Wolfram Föllmann

Journal:

Archives of Toxicology

Year:

2009

Language:

english

File:

PDF, 354 KB

english, 2009

33

Synergism of aromatic amines and benzo[a]pyrene in induction of Ah receptor-dependent genes

Alexandra Borza, Sabine Plöttner, Alexander Wolf, Claudia Behm, Silvia Selinski, Jan G. Hengstler, Peter H. Roos, Hermann M. Bolt, Jürgen Kuhlmann, Wolfram Föllmann

Journal:

Archives of Toxicology

Year:

2008

Language:

english

File:

PDF, 379 KB

english, 2008

34

Low-dose extrapolation in toxicology: an old controversy revisited

Hermann M. Bolt, Rosemarie Marchan, Jan G. Hengstler

Journal:

Archives of Toxicology

Year:

2009

Language:

english

File:

PDF, 147 KB

english, 2009

35

Can drinking tea prevent cancer?

Jan G. Hengstler, Rosemarie Marchan, Hermann M. Bolt

Journal:

Archives of Toxicology

Year:

2009

Language:

english

File:

PDF, 139 KB

english, 2009

36

Editorial Manager System for online manuscript submission toArchives of Toxicology

Jan G. Hengstler, Hermann M. Bolt, Rosemarie Marchan

Journal:

Archives of Toxicology

Year:

2009

Language:

english

File:

PDF, 136 KB

english, 2009

37

A rapid and easy to handle thermoluminescence based technique for evaluation of carbon tetrachloride-induced oxidative stress on rat hepatocytes

Anika Schumann, Alexander Bauer, Matthias Hermes, Matthias Gilbert, Jan G. Hengstler, Christian Wilhelm

Journal:

Archives of Toxicology

Year:

2009

Language:

english

File:

PDF, 571 KB

english, 2009

38

Alcohol-induced liver injury: how a small molecule overwhelms one of the cell types with the best regeneration capacity of the human body

Jan G. Hengstler, Patricio Godoy, Joanna D. Stewart, Hermann M. Bolt

Journal:

Archives of Toxicology

Year:

2009

Language:

english

File:

PDF, 152 KB

english, 2009

39

Mechanisms of telomere maintenance and attrition: linking cancer and ageing

Jan G. Hengstler, Rosemarie Marchan, Hermann M. Bolt

Journal:

Archives of Toxicology

Year:

2009

Language:

english

File:

PDF, 168 KB

english, 2009

40

Predicting drug metabolism-dependent toxicity

Hermann M. Bolt, Jan G. Hengstler

Journal:

Archives of Toxicology

Year:

2009

Language:

english

File:

PDF, 130 KB

english, 2009

41

Oxidative stress and hepatic carcinogenesis: new insights and applications

Hermann M. Bolt, Jan G. Hengstler

Journal:

Archives of Toxicology

Year:

2010

Language:

english

File:

PDF, 116 KB

english, 2010

42

Gene array screening for identification of drugs with low levels of adverse side effects

Hermann M. Bolt, Rosemarie Marchan, Jan G. Hengstler

Journal:

Archives of Toxicology

Year:

2010

Language:

english

File:

PDF, 116 KB

english, 2010

43

The carcinogenicity debate on formaldehyde: How to derive safe exposure limits?

Hermann M. Bolt, Gisela H. Degen, Jan G. Hengstler

Journal:

Archives of Toxicology

Year:

2010

Language:

english

File:

PDF, 153 KB

english, 2010

44

A physiologically based toxicokinetic modelling approach to predict relevant concentrations for in vitro testing

Hans Mielke, Lennart T. Anger, Markus Schug, Jan G. Hengstler, Ralf Stahlmann, Ursula Gundert-Remy

Journal:

Archives of Toxicology

Year:

2011

Language:

english

File:

PDF, 259 KB

english, 2011

45

Genetic variants in urinary bladder cancer: collective power of the “wimp SNPs”

Klaus Golka, Silvia Selinski, Marie-Louise Lehmann, Meinolf Blaszkewicz, Rosemarie Marchan, Katja Ickstadt, Holger Schwender, Hermann M. Bolt, Jan G. Hengstler

Journal:

Archives of Toxicology

Year:

2011

Language:

english

File:

PDF, 745 KB

english, 2011

46

Highlight report: towards the replacement of in vivo repeated dose systemic toxicity testing

Jan G. Hengstler, Rosemarie Marchan, Marcel Leist

Journal:

Archives of Toxicology

Year:

2012

Language:

english

File:

PDF, 120 KB

english, 2012

47

Genotoxic risk for humans due to work place exposure to ethylene oxide: remarkable individual differences in susceptibility

Jürgen Fuchs, Ute Wullenweber, Jan Georg Hengstler, Heinz Günter Bienfait, Gerd Hiltl, Franz Oesch

Journal:

Archives of Toxicology

Year:

1994

Language:

english

File:

PDF, 736 KB

english, 1994

48

Control of the mutagenicity of arylamines by protein kinases and phosphatases: II. Lack of response of rat liver N-acetyl transferases to phosphorylation modulators

Palghat Raghunathan Padma, Barbara Oesch-Bartlomowicz, Jan Georg Hengstler, Franz Oesch

Journal:

Archives of Toxicology

Year:

1997

Language:

english

File:

PDF, 200 KB

english, 1997

49

Comparative metabolism of the designer drug 4-methylthioamphetamine by hepatocytes from man, monkey, dog, rabbit, rat and mouse

Helena Carmo, Jan G. Hengstler, Douwe de Boer, Michael Ringel, Félix Carvalho, Eduarda Fernandes, Fernando Remião, Lesseps A. dos Reys, Franz Oesch, Maria de Lourdes Bastos

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

2004

Language:

english

File:

PDF, 260 KB

english, 2004

50

Phenotype and growth behavior of residual β-catenin-positive hepatocytes in livers of β-catenin-deficient mice

Albert Braeuning, Yasmin Singh, Benjamin Rignall, Albrecht Buchmann, Seddik Hammad, Amnah Othman, Iris von Recklinghausen, Patricio Godoy, Stefan Hoehme, Dirk Drasdo, Jan G. Hengstler, Michael Schwarz

Journal:

Histochemistry and Cell Biology

Year:

2010

Language:

english

File:

PDF, 1.36 MB

english, 2010